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BDBM50477170 CHEMBL391576

SMILES: Cc1ncc(c(NC2CCCC2)n1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=FYCNJRZAIAGPQL-UHFFFAOYSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477170   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
GABA-B receptor 1/2


(Homo sapiens (Human))		BDBM50477170
PNG
(CHEMBL391576)
Show SMILES Cc1ncc(c(NC2CCCC2)n1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C17H18F3N3/c1-11-21-10-15(16(22-11)23-14-4-2-3-5-14)12-6-8-13(9-7-12)17(18,19)20/h6-10,14H,2-5H2,1H3,(H,21,22,23)
PDB

KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 5.01E+3n/an/an/an/a



Novartis Institutes for Biomedical Research

Curated by ChEMBL


Assay Description
Activity at GABAB 1b/2 receptor expressed in CHO-K1 cells assessed as effect on glutamate-induced [35S]GTP-gamma-S binding

Bioorg Med Chem Lett 17: 6206-11 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.023
BindingDB Entry DOI: 10.7270/Q2N300RD
More data for this
Ligand-Target Pair