BDBM50477505 CHEMBL248515

SMILES: CC(C)c1cc(Oc2c(C)cc3c(CC(O)=O)coc3c2C)ccc1O

InChI Key: InChIKey=XGIXEBKNKXHCMD-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477505   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid Hormone Receptor (TR-alpha)/(TR-beta) (Homo sapiens (Human))	BDBM50477505 (CHEMBL248515) Show SMILES CC(C)c1cc(Oc2c(C)cc3c(CC(O)=O)coc3c2C)ccc1O Show InChI InChI=1S/C21H22O5/c1-11(2)16-9-15(5-6-18(16)22)26-20-12(3)7-17-14(8-19(23)24)10-25-21(17)13(20)4/h5-7,9-11,22H,8H2,1-4H3,(H,23,24)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Agonist activity at THR in HepG2 cells by whole cell assay				Bioorg Med Chem Lett 17: 3992-6 (2007) Article DOI: 10.1016/j.bmcl.2007.04.085 BindingDB Entry DOI: 10.7270/Q2251N06
					More data for this Ligand-Target Pair