BDBM50477506 CHEMBL392666

SMILES: CC(C)c1cc(Oc2c(C)ccc(CC3CC(=O)NC(=O)S3)c2C)ccc1O

InChI Key: InChIKey=TWNAGPAVIUMOMK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477506   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid Hormone Receptor (TR-alpha)/(TR-beta) (Homo sapiens (Human))	BDBM50477506 (CHEMBL392666) Show SMILES CC(C)c1cc(Oc2c(C)ccc(CC3CC(=O)NC(=O)S3)c2C)ccc1O Show InChI InChI=1S/C22H25NO4S/c1-12(2)18-10-16(7-8-19(18)24)27-21-13(3)5-6-15(14(21)4)9-17-11-20(25)23-22(26)28-17/h5-8,10,12,17,24H,9,11H2,1-4H3,(H,23,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	0.0600	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Agonist activity at THR in HepG2 cells by whole cell assay				Bioorg Med Chem Lett 17: 3992-6 (2007) Article DOI: 10.1016/j.bmcl.2007.04.085 BindingDB Entry DOI: 10.7270/Q2251N06
					More data for this Ligand-Target Pair