BDBM50477509 CHEMBL395954

SMILES: CC(C)c1cc(Oc2c(Br)cc3oc(cc3c2Br)C(O)=O)ccc1O

InChI Key: InChIKey=VYQVOAZEEZYHRP-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477509   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid Hormone Receptor (TR-alpha)/(TR-beta) (Homo sapiens (Human))	BDBM50477509 (CHEMBL395954) Show SMILES CC(C)c1cc(Oc2c(Br)cc3oc(cc3c2Br)C(O)=O)ccc1O Show InChI InChI=1S/C18H14Br2O5/c1-8(2)10-5-9(3-4-13(10)21)24-17-12(19)7-14-11(16(17)20)6-15(25-14)18(22)23/h3-8,21H,1-2H3,(H,22,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Bayer HealthCare AG Curated by ChEMBL					Assay Description Agonist activity at THR in HepG2 cells by whole cell assay				Bioorg Med Chem Lett 17: 3992-6 (2007) Article DOI: 10.1016/j.bmcl.2007.04.085 BindingDB Entry DOI: 10.7270/Q2251N06
					More data for this Ligand-Target Pair