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SMILES: CSc1ccc2nc(cn2c1)-c1ccc(cc1)N(C)C

InChI Key: InChIKey=WOYCDVDURLTMAW-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477824   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50477824
PNG
(CHEMBL252766)
Show SMILES CSc1ccc2nc(cn2c1)-c1ccc(cc1)N(C)C
Show InChI InChI=1S/C16H17N3S/c1-18(2)13-6-4-12(5-7-13)15-11-19-10-14(20-3)8-9-16(19)17-15/h4-11H,1-3H3
PDB
MMDB

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PubMed
 7.90n/an/an/an/an/an/an/an/a



National Institute of Mental Health

Curated by ChEMBL


Assay Description
Binding affinity to beta amyloid plaque in human Alzheimer's disease brain tissue

J Med Chem 51: 148-58 (2008)


Article DOI: 10.1021/jm700970s
BindingDB Entry DOI: 10.7270/Q2BG2RSQ
More data for this
Ligand-Target Pair