BDBM50477954 CHEMBL252405

SMILES: Fc1cccc(Cl)c1CNC(=O)c1[nH]c2ccc(Br)cc2c1S(=O)(=O)N1CCCC1

InChI Key: InChIKey=NGKSRKYOGVIJBP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50477954   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase protein (Human immunodeficiency virus 1)	BDBM50477954 (CHEMBL252405) Show SMILES Fc1cccc(Cl)c1CNC(=O)c1[nH]c2ccc(Br)cc2c1S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C20H18BrClFN3O3S/c21-12-6-7-17-13(10-12)19(30(28,29)26-8-1-2-9-26)18(25-17)20(27)24-11-14-15(22)4-3-5-16(14)23/h3-7,10,25H,1-2,8-9,11H2,(H,24,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Inhibition of HIV NL43 recombinant reverse transcriptase K103N mutant by scintillation proximity assay				Bioorg Med Chem Lett 18: 554-9 (2008) Article DOI: 10.1016/j.bmcl.2007.11.085 BindingDB Entry DOI: 10.7270/Q2F76GBM
					More data for this Ligand-Target Pair