BDBM50479658 CHEMBL480562

SMILES: CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1

InChI Key: InChIKey=OSAYEFAVHIZKGG-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50479658   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase (Homo sapiens (Human))	BDBM50479658 (CHEMBL480562) Show SMILES CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C16H14ClNO4S2/c1-11(19)23-10-16(20)12-2-6-14(7-3-12)18-24(21,22)15-8-4-13(17)5-9-15/h2-9,18H,10H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
Kalypsys Inc Curated by ChEMBL					Assay Description Inhibition of histone deacetylase in human HeLa cells assessed as induction of histone H3 hyperacetylation				Bioorg Med Chem Lett 18: 6482-5 (2008) Article DOI: 10.1016/j.bmcl.2008.10.058 BindingDB Entry DOI: 10.7270/Q2G44T2P
					More data for this Ligand-Target Pair