BDBM50479862 CHEMBL489122

SMILES: Cn1cncc1[C@@](N)(c1cc2cc(cc(-c3ccccc3)c2o1)[N+]([O-])=O)c1ccc(cc1)C#N

InChI Key: InChIKey=XFLDZCZKAVQGOE-AREMUKBSSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50479862   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Homo sapiens (Human))	BDBM50479862 (CHEMBL489122) Show SMILES Cn1cncc1[C@@](N)(c1cc2cc(cc(-c3ccccc3)c2o1)[N+]([O-])=O)c1ccc(cc1)C#N |r| Show InChI InChI=1S/C26H19N5O3/c1-30-16-29-15-23(30)26(28,20-9-7-17(14-27)8-10-20)24-12-19-11-21(31(32)33)13-22(25(19)34-24)18-5-3-2-4-6-18/h2-13,15-16H,28H2,1H3/t26-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Chugai Pharmaceutical Co. Ltd. Curated by ChEMBL					Assay Description Inhibition of human FTase				Bioorg Med Chem Lett 19: 1753-7 (2009) Article DOI: 10.1016/j.bmcl.2009.01.074 BindingDB Entry DOI: 10.7270/Q28G8PGH
					More data for this Ligand-Target Pair