null

SMILES: Cn1c2c(Oc3ccc(NC(=O)Nc4cccc(c4)C(C)(C)C)c4ccccc34)ccnc2[nH]c1=O

InChI Key: InChIKey=DIKYFMVHLLRVPI-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50480107   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50480107 (CHEMBL496081) Show SMILES Cn1c2c(Oc3ccc(NC(=O)Nc4cccc(c4)C(C)(C)C)c4ccccc34)ccnc2[nH]c1=O Show InChI InChI=1S/C28H27N5O3/c1-28(2,3)17-8-7-9-18(16-17)30-26(34)31-21-12-13-22(20-11-6-5-10-19(20)21)36-23-14-15-29-25-24(23)33(4)27(35)32-25/h5-16H,1-4H3,(H,29,32,35)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of BRAF V600E mutant				J Med Chem 52: 3881-91 (2009) Article DOI: 10.1021/jm900242c BindingDB Entry DOI: 10.7270/Q2Z03BZ4
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50480107 (CHEMBL496081) Show SMILES Cn1c2c(Oc3ccc(NC(=O)Nc4cccc(c4)C(C)(C)C)c4ccccc34)ccnc2[nH]c1=O Show InChI InChI=1S/C28H27N5O3/c1-28(2,3)17-8-7-9-18(16-17)30-26(34)31-21-12-13-22(20-11-6-5-10-19(20)21)36-23-14-15-29-25-24(23)33(4)27(35)32-25/h5-16H,1-4H3,(H,29,32,35)(H2,30,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of BRAF V600E mutant-mediated ERK phosphorylation in human WM266.4 cells				J Med Chem 52: 3881-91 (2009) Article DOI: 10.1021/jm900242c BindingDB Entry DOI: 10.7270/Q2Z03BZ4
					More data for this Ligand-Target Pair