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BDBM50480357 CHEMBL475260

SMILES: [#6]-[#8]-c1noc2c(-[#6])cc(cc12)-[#6](=[#6]/[#6]-[#6]-[#7]-1-[#6]-[#6]-[#8]-[#6]-1=O)\c1cc(-[#6])c2onc(-[#8]-[#6])c2c1

InChI Key: InChIKey=KQTPPDXXSDECOK-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50480357   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50480357
PNG
(CHEMBL475260)
Show SMILES [#6]-[#8]-c1noc2c(-[#6])cc(cc12)-[#6](=[#6]/[#6]-[#6]-[#7]-1-[#6]-[#6]-[#8]-[#6]-1=O)\c1cc(-[#6])c2onc(-[#8]-[#6])c2c1
Show InChI InChI=1S/C25H25N3O6/c1-14-10-16(12-19-21(14)33-26-23(19)30-3)18(6-5-7-28-8-9-32-25(28)29)17-11-15(2)22-20(13-17)24(31-4)27-34-22/h6,10-13H,5,7-9H2,1-4H3
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 930n/an/an/an/an/an/a



Purdue University

Curated by ChEMBL


Assay Description
Inhibition of HIV1 recombinant reverse transcriptase assessed as incorporation of [32P]GTP into poly(rC).oligo(dG) (rCdG) homopolymer template primer

Eur J Med Chem 44: 1210-4 (2009)


Article DOI: 10.1016/j.ejmech.2008.09.013
BindingDB Entry DOI: 10.7270/Q20R9S6T
More data for this
Ligand-Target Pair