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BDBM50481360 CHEMBL591550

SMILES: FC(F)(F)c1cc(CNCCCNc2ccc(Cl)cc2)cc(c1)C(F)(F)F

InChI Key: InChIKey=WTSHNZGKOWONII-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50481360   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-related GTP-binding protein RhoC


(Homo sapiens)		BDBM50481360
PNG
(CHEMBL591550)
Show SMILES FC(F)(F)c1cc(CNCCCNc2ccc(Cl)cc2)cc(c1)C(F)(F)F
Show InChI InChI=1S/C18H17ClF6N2/c19-15-2-4-16(5-3-15)27-7-1-6-26-11-12-8-13(17(20,21)22)10-14(9-12)18(23,24)25/h2-5,8-10,26-27H,1,6-7,11H2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.10E+3n/an/an/an/an/an/a



University of Michigan Medical School

Curated by ChEMBL


Assay Description
Inhibition of RhoA/C-mediated transcriptional response in human PC3 cells by serum response factor-luciferase reporter gene assay

Bioorg Med Chem Lett 20: 665-72 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.056
BindingDB Entry DOI: 10.7270/Q29S1TTD
More data for this
Ligand-Target Pair