BDBM50481433 CHEMBL591933
SMILES: [H][C@@]12CCCC[C@]1([H])CN(C[C@@H](O)[C@H](Cc1cc3ccccc3s1)NC(=O)c1cccc(O)c1C)[C@@H](C2)C(=O)NC(C)(C)C
InChI Key: InChIKey=FDKCMKCKCOAXOX-HQGUKNTCSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Protease (Human immunodeficiency virus 1 (HIV-1)) | BDBM50481433![]() (CHEMBL591933) | PDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi della Basilicata Curated by ChEMBL | Assay Description Inhibition of recombinant wild type HIV1 protease assessed as hydrolysis of fluorogenic substrate | J Med Chem 53: 1451-7 (2010) Article DOI: 10.1021/jm900846f BindingDB Entry DOI: 10.7270/Q2P271XP | |||||||||||
More data for this Ligand-Target Pair |