BDBM50481449 CHEMBL599408

SMILES: O=C(CN1CCN(CC1)C(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1

InChI Key: InChIKey=QXNYWQVYZYCACA-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50481449   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit beta-1/N-type calcium channel subunit alpha-1B/calcium channel subunit alpha-2/delta-1 (Rattus norvegicus-Rattus norvegicus (Rat))	BDBM50481449 (CHEMBL599408) Show SMILES O=C(CN1CCN(CC1)C(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-30(34(28-17-9-3-10-18-28)29-19-11-4-12-20-29)25-32-21-23-33(24-22-32)31(26-13-5-1-6-14-26)27-15-7-2-8-16-27/h1-20,31H,21-25H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of Calgary Curated by ChEMBL					Assay Description Blocking of rat N-type calcium channel alpha-1B/alpha-2-delta-1/beta-1b activity expressed in HEK293 cells assessed as whole cell current by whole ce...				Bioorg Med Chem Lett 19: 6467-72 (2009) Article DOI: 10.1016/j.bmcl.2009.09.008 BindingDB Entry DOI: 10.7270/Q2PV6P57
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C/L-type calcium channel subunit beta-1/calcium channel subunit alpha-2/delta-1 (Homo sapiens (Human))	BDBM50481449 (CHEMBL599408) Show SMILES O=C(CN1CCN(CC1)C(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-30(34(28-17-9-3-10-18-28)29-19-11-4-12-20-29)25-32-21-23-33(24-22-32)31(26-13-5-1-6-14-26)27-15-7-2-8-16-27/h1-20,31H,21-25H2	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neuromed Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of L-type calcium channel alpha-1c/alpha-2-delta-1/beta-1b expressed in HEK293 cells by FLIPR method				Bioorg Med Chem Lett 20: 1378-83 (2010) Article DOI: 10.1016/j.bmcl.2010.01.008 BindingDB Entry DOI: 10.7270/Q2DJ5JDR
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit beta-1 (Homo sapiens)	BDBM50481449 (CHEMBL599408) Show SMILES O=C(CN1CCN(CC1)C(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C31H31N3O/c35-30(34(28-17-9-3-10-18-28)29-19-11-4-12-20-29)25-32-21-23-33(24-22-32)31(26-13-5-1-6-14-26)27-15-7-2-8-16-27/h1-20,31H,21-25H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Neuromed Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of N type calcium channel alpha-1b/alpha-2-delta-1/beta-1b expressed in HEK293 cells at holding potential of -100 mV by whole-cell patch c...				Bioorg Med Chem Lett 20: 1378-83 (2010) Article DOI: 10.1016/j.bmcl.2010.01.008 BindingDB Entry DOI: 10.7270/Q2DJ5JDR
					More data for this Ligand-Target Pair