null

SMILES: C[C@@H](OC(=O)Nc1ccccc1)c1sc2ncnn2c1C

InChI Key: InChIKey=AOUUMBPBMVOBSP-SNVBAGLBSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50483144   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483144 (CHEMBL1630057 | GSK2210875) Show SMILES C[C@@H](OC(=O)Nc1ccccc1)c1sc2ncnn2c1C |r| Show InChI InChI=1S/C14H14N4O2S/c1-9-12(21-13-15-8-16-18(9)13)10(2)20-14(19)17-11-6-4-3-5-7-11/h3-8,10H,1-2H3,(H,17,19)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+4	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mGluR5				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Mus musculus)	BDBM50483144 (CHEMBL1630057 | GSK2210875) Show SMILES C[C@@H](OC(=O)Nc1ccccc1)c1sc2ncnn2c1C |r| Show InChI InChI=1S/C14H14N4O2S/c1-9-12(21-13-15-8-16-18(9)13)10(2)20-14(19)17-11-6-4-3-5-7-11/h3-8,10H,1-2H3,(H,17,19)/t10-/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at mGluR5 in mouse astrocytes assessed as inhibition of L-quisqualate induced calcium release by FLIPR assay				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50483144 (CHEMBL1630057 | GSK2210875) Show SMILES C[C@@H](OC(=O)Nc1ccccc1)c1sc2ncnn2c1C |r| Show InChI InChI=1S/C14H14N4O2S/c1-9-12(21-13-15-8-16-18(9)13)10(2)20-14(19)17-11-6-4-3-5-7-11/h3-8,10H,1-2H3,(H,17,19)/t10-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Medicines Research Centre Curated by ChEMBL					Assay Description Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization				Bioorg Med Chem Lett 20: 7521-4 (2010) Article DOI: 10.1016/j.bmcl.2010.09.120 BindingDB Entry DOI: 10.7270/Q2KH0R5D
					More data for this Ligand-Target Pair