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SMILES: CC(OC(=O)Nc1ccccc1)c1oc2nc(Cl)nn2c1C

InChI Key: InChIKey=VWMLTODHNBXOFD-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483149   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Homo sapiens (Human))		BDBM50483149
PNG
(CHEMBL1630065)
Show SMILES CC(OC(=O)Nc1ccccc1)c1oc2nc(Cl)nn2c1C
Show InChI InChI=1S/C14H13ClN4O3/c1-8-11(22-13-17-12(15)18-19(8)13)9(2)21-14(20)16-10-6-4-3-5-7-10/h3-7,9H,1-2H3,(H,16,20)
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Medicines Research Centre

Curated by ChEMBL


Assay Description
Antagonist activity at human mGluR5 expressed in CHO cells assessed as doxycycline induced calcium mobilization

Bioorg Med Chem Lett 20: 7521-4 (2010)


Article DOI: 10.1016/j.bmcl.2010.09.120
BindingDB Entry DOI: 10.7270/Q2KH0R5D
More data for this
Ligand-Target Pair