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SMILES: CN(CCCc1cn(Cc2ccc(F)cc2)c2cnc3C(=O)N(O)CCc3c12)C(C)=O

InChI Key: InChIKey=JQLFKDORBLFBHG-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483869   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrase


(Human immunodeficiency virus 1)		BDBM50483869
PNG
(CHEMBL1773407)
Show SMILES CN(CCCc1cn(Cc2ccc(F)cc2)c2cnc3C(=O)N(O)CCc3c12)C(C)=O
Show InChI InChI=1S/C23H25FN4O3/c1-15(29)26(2)10-3-4-17-14-27(13-16-5-7-18(24)8-6-16)20-12-25-22-19(21(17)20)9-11-28(31)23(22)30/h5-8,12,14,31H,3-4,9-11,13H2,1-2H3
PDB

UniProtKB/TrEMBL

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 14n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of HIV-1 integrase strand transfer activity by scintillation proximity assay

J Med Chem 54: 3393-417 (2011)


Article DOI: 10.1021/jm200208d
BindingDB Entry DOI: 10.7270/Q2514236
More data for this
Ligand-Target Pair