BDBM50483990 CHEMBL1801900

SMILES: COc1ccc(cc1)C(=O)N1c2ccccc2Oc2ccc(Cl)cc12

InChI Key: InChIKey=ZRKYSTMNLJOHQT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50483990   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50483990 (CHEMBL1801900) Show SMILES COc1ccc(cc1)C(=O)N1c2ccccc2Oc2ccc(Cl)cc12 Show InChI InChI=1S/C20H14ClNO3/c1-24-15-9-6-13(7-10-15)20(23)22-16-4-2-3-5-18(16)25-19-11-8-14(21)12-17(19)22/h2-12H,1H3	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Westphalian Wilhelms-University Curated by ChEMBL					Assay Description Inhibition of pig tubulin polymerization determined after 45 mins at 37 degC by turbidimetric analysis				J Med Chem 54: 4247-63 (2011) Article DOI: 10.1021/jm200436t BindingDB Entry DOI: 10.7270/Q2BK1G7W
					More data for this Ligand-Target Pair