BDBM50484315 CHEMBL1834746

SMILES: Clc1ccc(cn1)C(=O)Nc1nnc(s1)-c1ccc2OCCOc2c1

InChI Key: InChIKey=PYGRVEHCWINBCC-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50484315 (CHEMBL1834746) Show SMILES Clc1ccc(cn1)C(=O)Nc1nnc(s1)-c1ccc2OCCOc2c1 Show InChI InChI=1S/C16H11ClN4O3S/c17-13-4-2-10(8-18-13)14(22)19-16-21-20-15(25-16)9-1-3-11-12(7-9)24-6-5-23-11/h1-4,7-8H,5-6H2,(H,19,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.73E+4	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of human recombinant full-length FAK assessed as remaining ATP after 4 hrs by Kinase-Glo-luminescence assay				Bioorg Med Chem Lett 21: 6116-21 (2011) Article DOI: 10.1016/j.bmcl.2011.08.039 BindingDB Entry DOI: 10.7270/Q23T9M31
					More data for this Ligand-Target Pair