BindingDB logo
myBDB logout

BDBM50484324 CHEMBL1835515

SMILES: Cc1cc(C)cc(c1)C(=O)c1cc(Cl)ccc1OCCn1c(C)cc(=O)[nH]c1=O

InChI Key: InChIKey=ZRGDGBXCSXMXGX-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484324   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50484324
PNG
(CHEMBL1835515)
Show SMILES Cc1cc(C)cc(c1)C(=O)c1cc(Cl)ccc1OCCn1c(C)cc(=O)[nH]c1=O
Show InChI InChI=1S/C22H21ClN2O4/c1-13-8-14(2)10-16(9-13)21(27)18-12-17(23)4-5-19(18)29-7-6-25-15(3)11-20(26)24-22(25)28/h4-5,8-12H,6-7H2,1-3H3,(H,24,26,28)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 1.70E+3n/an/an/an/an/an/an/an/a



Volgograd State Medical University

Curated by ChEMBL


Assay Description
Inhibition of RNA-dependent DNA polymerase activity of HIV1 reverse transcriptase p66/p51 heterodimer using [8-3H]dGTP as substrate after 30 mins by ...

Bioorg Med Chem 19: 5794-802 (2011)


Article DOI: 10.1016/j.bmc.2011.08.025
BindingDB Entry DOI: 10.7270/Q2057JRG
More data for this
Ligand-Target Pair