BDBM50484446 CHEMBL1915843

SMILES: COc1cc(OC)cc(c1)C(=CC(C)=O)c1ccc(OC)c(OC)c1

InChI Key: InChIKey=HPYBFHOINKPXAH-LSCVHKIXSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50484446 (CHEMBL1915843) Show SMILES COc1cc(OC)cc(c1)C(=CC(C)=O)c1ccc(OC)c(OC)c1 Show InChI InChI=1S/C20H22O5/c1-13(21)8-18(14-6-7-19(24-4)20(11-14)25-5)15-9-16(22-2)12-17(10-15)23-3/h6-12H,1-5H3/b18-8-	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of human PDE4 expressed in U937 cells using [3H]cAMP as substrate after 30 mins				Bioorg Med Chem 19: 6356-74 (2011) Article DOI: 10.1016/j.bmc.2011.08.068 BindingDB Entry DOI: 10.7270/Q2Z60RXK
					More data for this Ligand-Target Pair