BindingDB logo
myBDB logout

null

SMILES: CN(CCF)c1ccc(\C=C/c2nc3ccccc3n2C)cc1

InChI Key: InChIKey=UHPBMWZEPJHUOQ-XFXZXTDPSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484503   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Amyloid-beta precursor protein


(Homo sapiens (Human))		BDBM50484503
PNG
(CHEMBL1926774)
Show SMILES CN(CCF)c1ccc(\C=C/c2nc3ccccc3n2C)cc1
Show InChI InChI=1S/C19H20FN3/c1-22(14-13-20)16-10-7-15(8-11-16)9-12-19-21-17-5-3-4-6-18(17)23(19)2/h3-12H,13-14H2,1-2H3/b12-9-
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 3.5n/an/an/an/an/a



Instituto Tecnol£gico e Nuclear

Curated by ChEMBL


Assay Description
Binding affinity to human amyloid beta (1 to 42) fibril by fluorescence intensity assay

Bioorg Med Chem 19: 7698-710 (2011)


Article DOI: 10.1016/j.bmc.2011.09.065
BindingDB Entry DOI: 10.7270/Q2X63QTN
More data for this
Ligand-Target Pair