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BDBM50484512 CHEMBL1928157

SMILES: Cc1c(nnn1Cc1ccc(F)cc1)C(=O)\C=C(/O)c1ccccc1

InChI Key: InChIKey=XJTWSMFPNQLQKN-BOPFTXTBSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484512   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrase


(Human immunodeficiency virus 1)		BDBM50484512
PNG
(CHEMBL1928157)
Show SMILES Cc1c(nnn1Cc1ccc(F)cc1)C(=O)\C=C(/O)c1ccccc1
Show InChI InChI=1S/C19H16FN3O2/c1-13-19(18(25)11-17(24)15-5-3-2-4-6-15)21-22-23(13)12-14-7-9-16(20)10-8-14/h2-11,24H,12H2,1H3/b17-11-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>5.90E+4n/an/an/an/an/an/a



Beijing University of Technology

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus 1 integrase-mediated strand transfer activity after 1 hr

Bioorg Med Chem 20: 177-82 (2012)


Article DOI: 10.1016/j.bmc.2011.11.014
BindingDB Entry DOI: 10.7270/Q2NP278N
More data for this
Ligand-Target Pair