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SMILES: Cc1c(nnn1Cc1ccc(F)cc1)C(=O)\C=C(/O)c1cc(O)c(O)c(O)c1

InChI Key: InChIKey=IOLMLGBFOBIELW-ZSOIEALJSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50484517   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Integrase


(Human immunodeficiency virus 1)		BDBM50484517
PNG
(CHEMBL1928167)
Show SMILES Cc1c(nnn1Cc1ccc(F)cc1)C(=O)\C=C(/O)c1cc(O)c(O)c(O)c1
Show InChI InChI=1S/C19H16FN3O5/c1-10-18(21-22-23(10)9-11-2-4-13(20)5-3-11)15(25)8-14(24)12-6-16(26)19(28)17(27)7-12/h2-8,24,26-28H,9H2,1H3/b14-8-
PDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.60E+3n/an/an/an/an/an/a



Beijing University of Technology

Curated by ChEMBL


Assay Description
Inhibition of Human immunodeficiency virus 1 integrase-mediated strand transfer activity after 1 hr

Bioorg Med Chem 20: 177-82 (2012)


Article DOI: 10.1016/j.bmc.2011.11.014
BindingDB Entry DOI: 10.7270/Q2NP278N
More data for this
Ligand-Target Pair