BDBM50485035 CHEMBL2024561

SMILES: CC(C)(C)c1[nH]cnc1\C=c1/[nH]c(=O)\c(=C\c2cccc(c2)C(=O)c2ccccc2)[nH]c1=O

InChI Key: InChIKey=UOGLYILRMWEYRW-NMGXZBPKSA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485035   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50485035 (CHEMBL2024561) Show SMILES CC(C)(C)c1[nH]cnc1\C=c1/[nH]c(=O)\c(=C\c2cccc(c2)C(=O)c2ccccc2)[nH]c1=O Show InChI InChI=1S/C26H24N4O3/c1-26(2,3)23-19(27-15-28-23)14-21-25(33)29-20(24(32)30-21)13-16-8-7-11-18(12-16)22(31)17-9-5-4-6-10-17/h4-15H,1-3H3,(H,27,28)(H,29,33)(H,30,32)/b20-13-,21-14-	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL					Assay Description Binding affinity to porcine tubulin after 1 hr by spectrofluorometric analysis				J Med Chem 55: 1056-71 (2012) Article DOI: 10.1021/jm2009088 BindingDB Entry DOI: 10.7270/Q20R9S8Q
					More data for this Ligand-Target Pair