null

SMILES: CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(OC(C)C)nn3c2)c1F

InChI Key: InChIKey=QZOFILITMYVOIR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50485106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50485106 (CHEMBL2030240) Show SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(OC(C)C)nn3c2)c1F Show InChI InChI=1S/C19H21F2N5O4S/c1-4-7-31(28,29)25-14-6-5-13(20)17(18(14)21)19(27)23-12-9-22-15-8-16(30-11(2)3)24-26(15)10-12/h5-6,8-11,25H,4,7H2,1-3H3,(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	149	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. Curated by ChEMBL					Assay Description Inhibition of full-length B-raf V600E mutant				Bioorg Med Chem Lett 22: 1165-8 (2012) Article DOI: 10.1016/j.bmcl.2011.11.092 BindingDB Entry DOI: 10.7270/Q2RB77GQ
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase B-raf (Homo sapiens (Human))	BDBM50485106 (CHEMBL2030240) Show SMILES CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(OC(C)C)nn3c2)c1F Show InChI InChI=1S/C19H21F2N5O4S/c1-4-7-31(28,29)25-14-6-5-13(20)17(18(14)21)19(27)23-12-9-22-15-8-16(30-11(2)3)24-26(15)10-12/h5-6,8-11,25H,4,7H2,1-3H3,(H,23,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	449	n/a	n/a	n/a	n/a	n/a	n/a
Array BioPharma, Inc. Curated by ChEMBL					Assay Description Inhibition of B-raf V600E mutant-mediated Erk phosphorylation in human Malme3 cells				Bioorg Med Chem Lett 22: 1165-8 (2012) Article DOI: 10.1016/j.bmcl.2011.11.092 BindingDB Entry DOI: 10.7270/Q2RB77GQ
					More data for this Ligand-Target Pair