BDBM50485338 CHEMBL2046742
SMILES: Cc1ccc(CNS(=O)(=O)N2CCN(CC2)C(\C=N)=C(/OCC2(C)CC2)C(=O)Nc2cccc(Cl)c2)cc1N
InChI Key: InChIKey=HKDMLGUOJQXJFG-MDCBPPBZSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta-1,3-glucan synthase (Candida albicans) | BDBM50485338 (CHEMBL2046742) | UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Albany Molecular Research, Inc. (AMRI) Curated by ChEMBL | Assay Description Inhibition of glucan synthase in Candida albicans BWP17 membrane | Bioorg Med Chem Lett 22: 4896-9 (2012) Article DOI: 10.1016/j.bmcl.2012.04.127 BindingDB Entry DOI: 10.7270/Q2NC6424 | |||||||||||
More data for this Ligand-Target Pair |