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SMILES: OC(COc1ccccc1C(=O)c1ccccc1)CN1CCOCC1

InChI Key: InChIKey=GAOVJQOWJLABCV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485453   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50485453
PNG
(CHEMBL2057229)
Show SMILES OC(COc1ccccc1C(=O)c1ccccc1)CN1CCOCC1
Show InChI InChI=1S/C20H23NO4/c22-17(14-21-10-12-24-13-11-21)15-25-19-9-5-4-8-18(19)20(23)16-6-2-1-3-7-16/h1-9,17,22H,10-15H2
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.34E+4n/an/an/an/an/an/a



University of Vienna

Curated by ChEMBL


Assay Description
Inhibition of P-glycoprotein-mediated daunorubicin efflux from human CCRF-CEM/VCR1000 cells after 240 secs by FACS flow cytometric analysis

J Med Chem 55: 3261-73 (2012)


Article DOI: 10.1021/jm201705f
BindingDB Entry DOI: 10.7270/Q2ZP48ZK
More data for this
Ligand-Target Pair