null
SMILES: COc1ccc2\C(=C/c3ccc(OC)c(OC)c3)C(=O)CCc2c1
InChI Key: InChIKey=YAAKDZWIARJLIL-LICLKQGHSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tubulin beta chain (Sus scrofa) | BDBM50485663 (CHEMBL2153133) | PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Second Military Medical University Curated by ChEMBL | Assay Description Inhibition of porcine brain tubulin assembly measured every 1 min for 60 mins by turbidimetric analysis | J Med Chem 55: 5720-33 (2012) Article DOI: 10.1021/jm300596s BindingDB Entry DOI: 10.7270/Q2Z89G8V | |||||||||||
More data for this Ligand-Target Pair |