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BDBM50485664 CHEMBL2153155

SMILES: COc1ccc2CCC(=O)\C(=C\c3cc(OC)c(OC)c(OC)c3)c2c1

InChI Key: InChIKey=VZEAHISUVMTYPJ-RQZCQDPDSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485664   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tubulin beta chain


(Sus scrofa)		BDBM50485664
PNG
(CHEMBL2153155)
Show SMILES COc1ccc2CCC(=O)\C(=C\c3cc(OC)c(OC)c(OC)c3)c2c1
Show InChI InChI=1S/C21H22O5/c1-23-15-7-5-14-6-8-18(22)17(16(14)12-15)9-13-10-19(24-2)21(26-4)20(11-13)25-3/h5,7,9-12H,6,8H2,1-4H3/b17-9+
PDB

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.63E+3n/an/an/an/an/an/a



Second Military Medical University

Curated by ChEMBL


Assay Description
Inhibition of porcine brain tubulin assembly measured every 1 min for 60 mins by turbidimetric analysis

J Med Chem 55: 5720-33 (2012)


Article DOI: 10.1021/jm300596s
BindingDB Entry DOI: 10.7270/Q2Z89G8V
More data for this
Ligand-Target Pair