BDBM50485666 CHEMBL2152995

SMILES: COc1ccc(\C=C2\C(=O)CCc3cc(OC)ccc23)cc1

InChI Key: InChIKey=WTTZUKYOPYCHRW-WOJGMQOQSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485666   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50485666 (CHEMBL2152995) Show SMILES COc1ccc(\C=C2\C(=O)CCc3cc(OC)ccc23)cc1 Show InChI InChI=1S/C19H18O3/c1-21-15-6-3-13(4-7-15)11-18-17-9-8-16(22-2)12-14(17)5-10-19(18)20/h3-4,6-9,11-12H,5,10H2,1-2H3/b18-11+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin assembly measured every 1 min for 60 mins by turbidimetric analysis				J Med Chem 55: 5720-33 (2012) Article DOI: 10.1021/jm300596s BindingDB Entry DOI: 10.7270/Q2Z89G8V
					More data for this Ligand-Target Pair