BDBM50485667 CHEMBL2152992

SMILES: COc1cccc2\C(=C/c3cc(OC)c(OC)c(OC)c3)C(=O)CCc12

InChI Key: InChIKey=KDDUUHJBECPCEH-MHWRWJLKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tubulin beta chain (Sus scrofa)	BDBM50485667 (CHEMBL2152992) Show SMILES COc1cccc2\C(=C/c3cc(OC)c(OC)c(OC)c3)C(=O)CCc12 Show InChI InChI=1S/C21H22O5/c1-23-18-7-5-6-14-15(18)8-9-17(22)16(14)10-13-11-19(24-2)21(26-4)20(12-13)25-3/h5-7,10-12H,8-9H2,1-4H3/b16-10+	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of porcine brain tubulin assembly measured every 1 min for 60 mins by turbidimetric analysis				J Med Chem 55: 5720-33 (2012) Article DOI: 10.1021/jm300596s BindingDB Entry DOI: 10.7270/Q2Z89G8V
					More data for this Ligand-Target Pair