BDBM50485993 CHEMBL2203387

SMILES: Cn1ncc2cc(cnc12)-c1nc2ccc(F)nc2o1

InChI Key: InChIKey=FTXJKQAXQCMHKY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta amyloid A4 protein (Homo sapiens (Human))	BDBM50485993 (CHEMBL2203387) Show SMILES Cn1ncc2cc(cnc12)-c1nc2ccc(F)nc2o1 Show InChI InChI=1S/C13H8FN5O/c1-19-11-7(6-16-19)4-8(5-15-11)12-17-9-2-3-10(14)18-13(9)20-12/h2-6H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human amyloid beta plaque				ACS Med Chem Lett 2: 498-502 (2011) Article DOI: 10.1021/ml200018n BindingDB Entry DOI: 10.7270/Q2TB19RG
					More data for this Ligand-Target Pair