BDBM50485998 CHEMBL2203390

SMILES: Cn1ncc2cc(ccc12)-c1nc2ccc(F)nc2o1

InChI Key: InChIKey=SSBNWYWLOAHQKX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50485998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta amyloid A4 protein (Homo sapiens (Human))	BDBM50485998 (CHEMBL2203390) Show SMILES Cn1ncc2cc(ccc12)-c1nc2ccc(F)nc2o1 Show InChI InChI=1S/C14H9FN4O/c1-19-11-4-2-8(6-9(11)7-16-19)13-17-10-3-5-12(15)18-14(10)20-13/h2-7H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to human amyloid beta plaque				ACS Med Chem Lett 2: 498-502 (2011) Article DOI: 10.1021/ml200018n BindingDB Entry DOI: 10.7270/Q2TB19RG
					More data for this Ligand-Target Pair