BDBM50486798 CHEMBL2236212

SMILES: CCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCc1ccccc1

InChI Key: InChIKey=PTGNGDXCVQAGJU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50486798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Voltage-dependent L-type calcium channel subunit alpha-1C (Cavia porcellus)	BDBM50486798 (CHEMBL2236212) Show SMILES CCOC(=O)C1=C(C)NC(C)=C(C1c1cnc(SC)n1Nc1ccccc1)C(=O)OCc1ccccc1 |c:5,10| Show InChI InChI=1S/C28H30N4O4S/c1-5-35-26(33)23-18(2)30-19(3)24(27(34)36-17-20-12-8-6-9-13-20)25(23)22-16-29-28(37-4)32(22)31-21-14-10-7-11-15-21/h6-16,25,30-31H,5,17H2,1-4H3	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at Cavia porcellus albino (guinea pig) calcium channel assessed as inhibition of KCl-induced ileal longitudinal smooth muscle con...				Citation and Details Article DOI: 10.1007/s00044-011-9807-x BindingDB Entry DOI: 10.7270/Q20K2CFM
					More data for this Ligand-Target Pair