BDBM50488443 CHEMBL2286420

SMILES: CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1C(F)(F)F

InChI Key: InChIKey=BHSQODKUEYDLIS-UHFFFAOYSA-N

Data: 5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50488443   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ecdysone receptor (Bombyx mori)	BDBM50488443 (CHEMBL2286420) Show SMILES CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19F3N2O2/c1-18(2,3)24(23-16(25)13-9-5-4-6-10-13)17(26)14-11-7-8-12-15(14)19(20,21)22/h4-12H,1-3H3,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	871	n/a	n/a	n/a	n/a
Ghent University Curated by ChEMBL					Assay Description Agonist activity at ecdysone receptor in Bombyx mori Bm5 cells after 24 hr by luciferase reporter gene assay				Pest Manag Sci 66: 526-35 (2010) Article DOI: 10.1002/ps.1903 BindingDB Entry DOI: 10.7270/Q2KK9FPH
					More data for this Ligand-Target Pair
Ecdysone receptor (Spodoptera littoralis)	BDBM50488443 (CHEMBL2286420) Show SMILES CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19F3N2O2/c1-18(2,3)24(23-16(25)13-9-5-4-6-10-13)17(26)14-11-7-8-12-15(14)19(20,21)22/h4-12H,1-3H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
Ghent University Curated by ChEMBL					Assay Description Agonist activity at ecdysone receptor in Spodoptera littoralis Sl2 cells after 24 hr by luciferase reporter gene assay				Pest Manag Sci 66: 526-35 (2010) Article DOI: 10.1002/ps.1903 BindingDB Entry DOI: 10.7270/Q2KK9FPH
					More data for this Ligand-Target Pair
Protein ultraspiracle (Drosophila melanogaster)	BDBM50488443 (CHEMBL2286420) Show SMILES CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19F3N2O2/c1-18(2,3)24(23-16(25)13-9-5-4-6-10-13)17(26)14-11-7-8-12-15(14)19(20,21)22/h4-12H,1-3H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a
Ghent University Curated by ChEMBL					Assay Description Agonist activity at ecdysone receptor in Drosophila melanogaster S2 cells after 24 hr by luciferase reporter gene assay				Pest Manag Sci 66: 1215-29 (2010) Article DOI: 10.1002/ps.1998 BindingDB Entry DOI: 10.7270/Q2FT8PXB
					More data for this Ligand-Target Pair
Ecdysone receptor (Bombyx mori)	BDBM50488443 (CHEMBL2286420) Show SMILES CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19F3N2O2/c1-18(2,3)24(23-16(25)13-9-5-4-6-10-13)17(26)14-11-7-8-12-15(14)19(20,21)22/h4-12H,1-3H3,(H,23,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	631	n/a	n/a	n/a	n/a
Ghent University Curated by ChEMBL					Assay Description Agonist activity at ecdysone receptor in Bombyx mori Bm5 cells after 24 hr by luciferase reporter gene assay				Pest Manag Sci 66: 1215-29 (2010) Article DOI: 10.1002/ps.1998 BindingDB Entry DOI: 10.7270/Q2FT8PXB
					More data for this Ligand-Target Pair
Protein ultraspiracle (Drosophila melanogaster)	BDBM50488443 (CHEMBL2286420) Show SMILES CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1C(F)(F)F Show InChI InChI=1S/C19H19F3N2O2/c1-18(2,3)24(23-16(25)13-9-5-4-6-10-13)17(26)14-11-7-8-12-15(14)19(20,21)22/h4-12H,1-3H3,(H,23,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	3.63E+3	n/a	n/a	n/a	n/a
Ghent University Curated by ChEMBL					Assay Description Agonist activity at ecdysone receptor in Drosophila melanogaster B2 cells assessed as reduction in cell density				Pest Manag Sci 66: 1215-29 (2010) Article DOI: 10.1002/ps.1998 BindingDB Entry DOI: 10.7270/Q2FT8PXB
					More data for this Ligand-Target Pair