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BDBM50490643 CHEMBL2337196

SMILES: Cc1cc(Br)cc(Cn2c(=O)ccn(C\C=C\c3ccccc3)c2=O)c1

InChI Key: InChIKey=BVJWVIGIGGQCSG-VMPITWQZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490643   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50490643
PNG
(CHEMBL2337196)
Show SMILES Cc1cc(Br)cc(Cn2c(=O)ccn(C\C=C\c3ccccc3)c2=O)c1
Show InChI InChI=1S/C21H19BrN2O2/c1-16-12-18(14-19(22)13-16)15-24-20(25)9-11-23(21(24)26)10-5-8-17-6-3-2-4-7-17/h2-9,11-14H,10,15H2,1H3/b8-5+
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 310n/an/an/an/an/an/an/an/a



Volgograd State Medical University

Curated by ChEMBL


Assay Description
Non-competitive inhibition of wild type HIV1 reverse transcriptase p66/p51 after 30 mins by liquid scintillation counting

Bioorg Med Chem 21: 1150-8 (2013)


Article DOI: 10.1016/j.bmc.2012.12.027
BindingDB Entry DOI: 10.7270/Q2NZ8BKZ
More data for this
Ligand-Target Pair