null
SMILES: CCNC(=O)Nc1nc2ccc(cc2s1)-c1ccc(N)cc1OC
InChI Key: InChIKey=XDGXRHXJQURQOE-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosine-protein kinase ABL1 (Homo sapiens (Human)) | BDBM50490890 (CHEMBL2347719) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology (KAIST) Curated by ChEMBL | Assay Description Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase... | J Med Chem 56: 3531-45 (2013) Article DOI: 10.1021/jm301891t BindingDB Entry DOI: 10.7270/Q2BG2RW2 | |||||||||||
More data for this Ligand-Target Pair |