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SMILES: CCNC(=O)Nc1nc2ccc(cc2[nH]1)-c1ccccc1Cl

InChI Key: InChIKey=JBVZJUHTCXXPSZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50490906   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase ABL1


(Homo sapiens (Human))		BDBM50490906
PNG
(CHEMBL2347737)
Show SMILES CCNC(=O)Nc1nc2ccc(cc2[nH]1)-c1ccccc1Cl
Show InChI InChI=1S/C16H15ClN4O/c1-2-18-16(22)21-15-19-13-8-7-10(9-14(13)20-15)11-5-3-4-6-12(11)17/h3-9H,2H2,1H3,(H3,18,19,20,21,22)
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n/an/a 21n/an/an/an/an/an/a



Korea Institute of Science and Technology (KAIST)

Curated by ChEMBL


Assay Description
Inhibition of breakpoint cluster region-Abelson tyrosine kinase T315I mutant (unknown origin) using [gamma-33P]ATP as substrate by radiometric kinase...

J Med Chem 56: 3531-45 (2013)


Article DOI: 10.1021/jm301891t
BindingDB Entry DOI: 10.7270/Q2BG2RW2
More data for this
Ligand-Target Pair