null
SMILES: OC(=O)CCc1ccc(Nc2nc(nc3CS(=O)(=O)Cc23)-c2ccccc2)cc1
InChI Key: InChIKey=CYYQJYKSCWJWCW-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human)) | BDBM50491743 (CHEMBL2385565) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human recombinant PDE4B (152 to 564 amino acids) using cAMP as substrate after 30 mins by plate reader analysis | Bioorg Med Chem Lett 23: 3325-8 (2013) Article DOI: 10.1016/j.bmcl.2013.03.104 BindingDB Entry DOI: 10.7270/Q2QF8WSQ | |||||||||||
More data for this Ligand-Target Pair |