BDBM50491873 CHEMBL2387617
SMILES: CCc1ccccc1S(=O)(=O)C1CO1
InChI Key: InChIKey=IWWMJBVIRHTALT-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin B (Homo sapiens (Human)) | BDBM50491873 (CHEMBL2387617) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | 8.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The City University of New York Curated by ChEMBL | Assay Description Inhibition of human liver cathepsin B using Z-RR-para-nitroanilide as substrate assessed as reversible equilibrium binding constant by Kitz-Wilson pl... | Bioorg Med Chem 21: 2975-87 (2013) Article DOI: 10.1016/j.bmc.2013.03.062 BindingDB Entry DOI: 10.7270/Q2PG1VNW | |||||||||||
More data for this Ligand-Target Pair |