BDBM50491927 CHEMBL2386105

SMILES: COCCn1cc(C2=C(C(=O)NC2=O)c2coc3ccccc23)c2cc(F)c(F)cc12

InChI Key: InChIKey=NXMQDCGRTSYYID-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491927   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50491927 (CHEMBL2386105) Show SMILES COCCn1cc(C2=C(C(=O)NC2=O)c2coc3ccccc23)c2cc(F)c(F)cc12 |t:7| Show InChI InChI=1S/C23H16F2N2O4/c1-30-7-6-27-10-14(13-8-16(24)17(25)9-18(13)27)20-21(23(29)26-22(20)28)15-11-31-19-5-3-2-4-12(15)19/h2-5,8-11H,6-7H2,1H3,(H,26,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Inhibition of human GSK3beta-mediated YRRAAVPPSPSLSRHSSPHQ(pS)EDEEE phosphorylation				J Med Chem 56: 5115-29 (2013) Article DOI: 10.1021/jm400511s BindingDB Entry DOI: 10.7270/Q21R6TFJ
					More data for this Ligand-Target Pair