BDBM50491998 CHEMBL2391649

SMILES: CC(C)N1c2c(F)cc(F)c(F)c2CC[C@@H](NC(=O)[C@@H](Cc2ccccc2OC(F)(F)F)NC(=O)OC(C)(C)C)C1=O

InChI Key: InChIKey=FFULJJKCXFNUHJ-WOJBJXKFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50491998   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50491998 (CHEMBL2391649) Show SMILES CC(C)N1c2c(F)cc(F)c(F)c2CC[C@@H](NC(=O)[C@@H](Cc2ccccc2OC(F)(F)F)NC(=O)OC(C)(C)C)C1=O |r| Show InChI InChI=1S/C28H31F6N3O5/c1-14(2)37-23-16(22(31)17(29)13-18(23)30)10-11-19(25(37)39)35-24(38)20(36-26(40)42-27(3,4)5)12-15-8-6-7-9-21(15)41-28(32,33)34/h6-9,13-14,19-20H,10-12H2,1-5H3,(H,35,38)(H,36,40)/t19-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of human NaV1.7 channel expressed in HEK293 cells by FRET assay				Bioorg Med Chem Lett 23: 3640-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.121 BindingDB Entry DOI: 10.7270/Q2W098VM
					More data for this Ligand-Target Pair