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SMILES: CC[C@H]1C[C@H](CCO1)n1c2c3cc(-c4cnn(C)c4)c(cc3oc2c(nc1=O)-c1cnn(C)c1)C#N

InChI Key: InChIKey=GYAFBLINDLEUJW-OALUTQOASA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50492167   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50492167
PNG
(CHEMBL2397558)
Show SMILES CC[C@H]1C[C@H](CCO1)n1c2c3cc(-c4cnn(C)c4)c(cc3oc2c(nc1=O)-c1cnn(C)c1)C#N |r|
Show InChI InChI=1S/C26H25N7O3/c1-4-19-8-18(5-6-35-19)33-24-21-9-20(16-11-28-31(2)13-16)15(10-27)7-22(21)36-25(24)23(30-26(33)34)17-12-29-32(3)14-17/h7,9,11-14,18-19H,4-6,8H2,1-3H3/t18-,19-/m0/s1
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PC cid
PC sid
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Article
PubMed
n/an/a 7n/an/an/an/an/an/a



Boehringer Ingelheim (Canada) Ltd

Curated by ChEMBL


Assay Description
Inhibition of HIV1 reverse transcriptase using poly(rA)/oligo(dT)15 as substrate after 60 mins by fluorescence assay

Bioorg Med Chem Lett 23: 3967-75 (2013)


Article DOI: 10.1016/j.bmcl.2013.04.043
BindingDB Entry DOI: 10.7270/Q26976HF
More data for this
Ligand-Target Pair