BDBM50492425 CHEMBL2401935

SMILES: Cl.COc1ccccc1N1CCN(Cc2ccc3oc4ccccc4c(=O)c3c2)CC1

InChI Key: InChIKey=ZOPHPUXNWRKATM-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50492425   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50492425 (CHEMBL2401935) Show SMILES Cl.COc1ccccc1N1CCN(Cc2ccc3oc4ccccc4c(=O)c3c2)CC1 Show InChI InChI=1S/C25H24N2O3/c1-29-24-9-5-3-7-21(24)27-14-12-26(13-15-27)17-18-10-11-23-20(16-18)25(28)19-6-2-4-8-22(19)30-23/h2-11,16H,12-15,17H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells after 1 hr				Bioorg Med Chem Lett 23: 4419-23 (2013) Article DOI: 10.1016/j.bmcl.2013.05.062 BindingDB Entry DOI: 10.7270/Q2SX6H5S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50492425 (CHEMBL2401935) Show SMILES Cl.COc1ccccc1N1CCN(Cc2ccc3oc4ccccc4c(=O)c3c2)CC1 Show InChI InChI=1S/C25H24N2O3/c1-29-24-9-5-3-7-21(24)27-14-12-26(13-15-27)17-18-10-11-23-20(16-18)25(28)19-6-2-4-8-22(19)30-23/h2-11,16H,12-15,17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	426	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5-CT from human 5HT7b receptor expressed in HEK293 cells after 1 hr				Bioorg Med Chem Lett 23: 4419-23 (2013) Article DOI: 10.1016/j.bmcl.2013.05.062 BindingDB Entry DOI: 10.7270/Q2SX6H5S
					More data for this Ligand-Target Pair
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50492425 (CHEMBL2401935) Show SMILES Cl.COc1ccccc1N1CCN(Cc2ccc3oc4ccccc4c(=O)c3c2)CC1 Show InChI InChI=1S/C25H24N2O3/c1-29-24-9-5-3-7-21(24)27-14-12-26(13-15-27)17-18-10-11-23-20(16-18)25(28)19-6-2-4-8-22(19)30-23/h2-11,16H,12-15,17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenergic receptor in rat cerebral cortex after 30 mins by scintillation counting				Bioorg Med Chem Lett 23: 4419-23 (2013) Article DOI: 10.1016/j.bmcl.2013.05.062 BindingDB Entry DOI: 10.7270/Q2SX6H5S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50492425 (CHEMBL2401935) Show SMILES Cl.COc1ccccc1N1CCN(Cc2ccc3oc4ccccc4c(=O)c3c2)CC1 Show InChI InChI=1S/C25H24N2O3/c1-29-24-9-5-3-7-21(24)27-14-12-26(13-15-27)17-18-10-11-23-20(16-18)25(28)19-6-2-4-8-22(19)30-23/h2-11,16H,12-15,17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.94E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1 hr				Bioorg Med Chem Lett 23: 4419-23 (2013) Article DOI: 10.1016/j.bmcl.2013.05.062 BindingDB Entry DOI: 10.7270/Q2SX6H5S
					More data for this Ligand-Target Pair