BDBM50492429 CHEMBL3215698

SMILES: Cl.Cl.Cl.CN1CCN(Cc2cccc3c2oc2cc(Cl)ccc2c3=O)CC1

InChI Key: InChIKey=RXSHWXGICAGMFZ-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50492429   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50492429 (CHEMBL3215698) Show SMILES Cl.Cl.Cl.CN1CCN(Cc2cccc3c2oc2cc(Cl)ccc2c3=O)CC1 Show InChI InChI=1S/C19H19ClN2O2/c1-21-7-9-22(10-8-21)12-13-3-2-4-16-18(23)15-6-5-14(20)11-17(15)24-19(13)16/h2-6,11H,7-10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	650	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenergic receptor in rat cerebral cortex after 30 mins by scintillation counting				Bioorg Med Chem Lett 23: 4419-23 (2013) Article DOI: 10.1016/j.bmcl.2013.05.062 BindingDB Entry DOI: 10.7270/Q2SX6H5S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50492429 (CHEMBL3215698) Show SMILES Cl.Cl.Cl.CN1CCN(Cc2cccc3c2oc2cc(Cl)ccc2c3=O)CC1 Show InChI InChI=1S/C19H19ClN2O2/c1-21-7-9-22(10-8-21)12-13-3-2-4-16-18(23)15-6-5-14(20)11-17(15)24-19(13)16/h2-6,11H,7-10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]5-CT from human 5HT7b receptor expressed in HEK293 cells after 1 hr				Bioorg Med Chem Lett 23: 4419-23 (2013) Article DOI: 10.1016/j.bmcl.2013.05.062 BindingDB Entry DOI: 10.7270/Q2SX6H5S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50492429 (CHEMBL3215698) Show SMILES Cl.Cl.Cl.CN1CCN(Cc2cccc3c2oc2cc(Cl)ccc2c3=O)CC1 Show InChI InChI=1S/C19H19ClN2O2/c1-21-7-9-22(10-8-21)12-13-3-2-4-16-18(23)15-6-5-14(20)11-17(15)24-19(13)16/h2-6,11H,7-10,12H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cells after 1 hr				Bioorg Med Chem Lett 23: 4419-23 (2013) Article DOI: 10.1016/j.bmcl.2013.05.062 BindingDB Entry DOI: 10.7270/Q2SX6H5S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50492429 (CHEMBL3215698) Show SMILES Cl.Cl.Cl.CN1CCN(Cc2cccc3c2oc2cc(Cl)ccc2c3=O)CC1 Show InChI InChI=1S/C19H19ClN2O2/c1-21-7-9-22(10-8-21)12-13-3-2-4-16-18(23)15-6-5-14(20)11-17(15)24-19(13)16/h2-6,11H,7-10,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Medical College Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5HT6 receptor expressed in HEK293 cells after 1 hr				Bioorg Med Chem Lett 23: 4419-23 (2013) Article DOI: 10.1016/j.bmcl.2013.05.062 BindingDB Entry DOI: 10.7270/Q2SX6H5S
					More data for this Ligand-Target Pair