BDBM50492441 CHEMBL2402544

SMILES: Cl.Clc1ccc(cc1)C1(CNC1)OCc1ccc(Cl)c(Cl)c1

InChI Key: InChIKey=MKCGEPXNEBRRAW-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50492441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Rattus norvegicus (rat))	BDBM50492441 (CHEMBL2402544) Show SMILES Cl.Clc1ccc(cc1)C1(CNC1)OCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H14Cl3NO/c17-13-4-2-12(3-5-13)16(9-20-10-16)21-8-11-1-6-14(18)15(19)7-11/h1-7,20H,8-10H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]Citalopram from SERT in Sprague-Dawley rat brain homogenate after 60 mins by scintillation counting analysis				Bioorg Med Chem Lett 23: 4404-7 (2013) Article DOI: 10.1016/j.bmcl.2013.05.071 BindingDB Entry DOI: 10.7270/Q2DN47ZV
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Rattus norvegicus (rat))	BDBM50492441 (CHEMBL2402544) Show SMILES Cl.Clc1ccc(cc1)C1(CNC1)OCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C16H14Cl3NO/c17-13-4-2-12(3-5-13)16(9-20-10-16)21-8-11-1-6-14(18)15(19)7-11/h1-7,20H,8-10H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of New Orleans Curated by ChEMBL					Assay Description Displacement of [3H]WIN 35,428 from DAT in Sprague-Dawley rat brain homogenate preincubated for 5 mins prior to radioligand addition measured after 1...				Bioorg Med Chem Lett 23: 4404-7 (2013) Article DOI: 10.1016/j.bmcl.2013.05.071 BindingDB Entry DOI: 10.7270/Q2DN47ZV
					More data for this Ligand-Target Pair