Found 6 hits for monomerid = 50492540 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Cereblon/Histone deacetylase 2
(Homo sapiens (Human)) | BDBM50492540
(CHEMBL2408243)Show InChI InChI=1S/C14H12O3/c1-17-12-7-5-10(6-8-12)11-3-2-4-13(15)14(16)9-11/h2-9H,1H3,(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 0.120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC2 by Michaelis-Menten equation analysis |
ACS Med Chem Lett 4: 757-61 (2013)
Article DOI: 10.1021/ml400158k BindingDB Entry DOI: 10.7270/Q28055HS |
More data for this Ligand-Target Pair | |
Histone deacetylase 8
(Homo sapiens (Human)) | BDBM50492540
(CHEMBL2408243)Show InChI InChI=1S/C14H12O3/c1-17-12-7-5-10(6-8-12)11-3-2-4-13(15)14(16)9-11/h2-9H,1H3,(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC8 by Michaelis-Menten equation analysis |
ACS Med Chem Lett 4: 757-61 (2013)
Article DOI: 10.1021/ml400158k BindingDB Entry DOI: 10.7270/Q28055HS |
More data for this Ligand-Target Pair | |
Histone deacetylase 5
(Homo sapiens (Human)) | BDBM50492540
(CHEMBL2408243)Show InChI InChI=1S/C14H12O3/c1-17-12-7-5-10(6-8-12)11-3-2-4-13(15)14(16)9-11/h2-9H,1H3,(H,15,16) | KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC5 by Michaelis-Menten equation analysis |
ACS Med Chem Lett 4: 757-61 (2013)
Article DOI: 10.1021/ml400158k BindingDB Entry DOI: 10.7270/Q28055HS |
More data for this Ligand-Target Pair | |
Cereblon/Histone deacetylase 1
(Homo sapiens (Human)) | BDBM50492540
(CHEMBL2408243)Show InChI InChI=1S/C14H12O3/c1-17-12-7-5-10(6-8-12)11-3-2-4-13(15)14(16)9-11/h2-9H,1H3,(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC1 by Michaelis-Menten equation analysis |
ACS Med Chem Lett 4: 757-61 (2013)
Article DOI: 10.1021/ml400158k BindingDB Entry DOI: 10.7270/Q28055HS |
More data for this Ligand-Target Pair | |
Cereblon/Histone deacetylase 6
(Homo sapiens (Human)) | BDBM50492540
(CHEMBL2408243)Show InChI InChI=1S/C14H12O3/c1-17-12-7-5-10(6-8-12)11-3-2-4-13(15)14(16)9-11/h2-9H,1H3,(H,15,16) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC6 by Michaelis-Menten equation analysis |
ACS Med Chem Lett 4: 757-61 (2013)
Article DOI: 10.1021/ml400158k BindingDB Entry DOI: 10.7270/Q28055HS |
More data for this Ligand-Target Pair | |
Cereblon/Histone deacetylase 4
(Homo sapiens (Human)) | BDBM50492540
(CHEMBL2408243)Show InChI InChI=1S/C14H12O3/c1-17-12-7-5-10(6-8-12)11-3-2-4-13(15)14(16)9-11/h2-9H,1H3,(H,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| 8.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Connecticut
Curated by ChEMBL
| Assay Description Inhibition of human recombinant HDAC4 by Michaelis-Menten equation analysis |
ACS Med Chem Lett 4: 757-61 (2013)
Article DOI: 10.1021/ml400158k BindingDB Entry DOI: 10.7270/Q28055HS |
More data for this Ligand-Target Pair | |