BDBM50493351 CHEMBL2425374

SMILES: COc1cccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc12

InChI Key: InChIKey=BIWCHVGMGDYNNS-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50493351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50493351 (CHEMBL2425374) Show SMILES COc1cccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc12 Show InChI InChI=1S/C20H23NO3/c1-22-18-6-4-5-13-9-17-15-11-20(24-3)19(23-2)10-14(15)7-8-21(17)12-16(13)18/h4-6,10-11,17H,7-9,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	363	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Valencia Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from dopamine D2 receptor in rat striatal membranes after 1 hr by liquid scintillation counting analysis				Eur J Med Chem 68: 150-66 (2013) Article DOI: 10.1016/j.ejmech.2013.07.036 BindingDB Entry DOI: 10.7270/Q2J1063R
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50493351 (CHEMBL2425374) Show SMILES COc1cccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc12 Show InChI InChI=1S/C20H23NO3/c1-22-18-6-4-5-13-9-17-15-11-20(24-3)19(23-2)10-14(15)7-8-21(17)12-16(13)18/h4-6,10-11,17H,7-9,12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	393	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Valencia Curated by ChEMBL					Assay Description Displacement of [3H]-raclopride from dopamine D2 receptor in rat striatal membranes after 1 hr by liquid scintillation counting analysis				Eur J Med Chem 68: 150-66 (2013) Article DOI: 10.1016/j.ejmech.2013.07.036 BindingDB Entry DOI: 10.7270/Q2J1063R
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50493351 (CHEMBL2425374) Show SMILES COc1cccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc12 Show InChI InChI=1S/C20H23NO3/c1-22-18-6-4-5-13-9-17-15-11-20(24-3)19(23-2)10-14(15)7-8-21(17)12-16(13)18/h4-6,10-11,17H,7-9,12H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.63E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Valencia Curated by ChEMBL					Assay Description Displacement of [3H]-SCH 23390 from dopamine D1 receptor in rat striatal membranes after 1 hr by liquid scintillation counting analysis				Eur J Med Chem 68: 150-66 (2013) Article DOI: 10.1016/j.ejmech.2013.07.036 BindingDB Entry DOI: 10.7270/Q2J1063R
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50493351 (CHEMBL2425374) Show SMILES COc1cccc2CC3N(CCc4cc(OC)c(OC)cc34)Cc12 Show InChI InChI=1S/C20H23NO3/c1-22-18-6-4-5-13-9-17-15-11-20(24-3)19(23-2)10-14(15)7-8-21(17)12-16(13)18/h4-6,10-11,17H,7-9,12H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Valencia Curated by ChEMBL					Assay Description Displacement of [3H]-SCH 23390 from dopamine D1 receptor in rat striatal membranes after 1 hr by liquid scintillation counting analysis				Eur J Med Chem 68: 150-66 (2013) Article DOI: 10.1016/j.ejmech.2013.07.036 BindingDB Entry DOI: 10.7270/Q2J1063R
					More data for this Ligand-Target Pair