BDBM50493527 CHEMBL2431541

SMILES: Fc1cc(ccc1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)N1CCN(CC1)S(=O)(=O)c1ccccc1

InChI Key: InChIKey=ZWFASLVCIYKVPI-HKBQPEDESA-N

Data: 1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493527   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sterol 14-alpha demethylase (CYP51) (Trypanosoma cruzi)	BDBM50493527 (CHEMBL2431541) Show SMILES Fc1cc(ccc1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)N1CCN(CC1)S(=O)(=O)c1ccccc1 |r| Show InChI InChI=1S/C33H31FN6O4S/c34-29-21-25(39-16-18-40(19-17-39)45(43,44)26-6-2-1-3-7-26)10-11-28(29)32(41)38-31(33(42)37-24-12-14-35-15-13-24)20-23-22-36-30-9-5-4-8-27(23)30/h1-15,21-22,31,36H,16-20H2,(H,38,41)(H,35,37,42)/t31-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	<5	n/a	n/a	n/a	n/a	n/a
Scripps Florida Curated by ChEMBL					Assay Description Binding affinity to recombinant Trypanosoma cruzi CYP51 expressed in Escherichia coli by UV-Vis spectrophotometric analysis				J Med Chem 56: 7651-68 (2013) Article DOI: 10.1021/jm401067s BindingDB Entry DOI: 10.7270/Q2TB19VT
					More data for this Ligand-Target Pair