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SMILES: CCc1c(nc(SCc2ccc(OC)cc2)[nH]c1=O)C(=O)c1cccc(F)c1

InChI Key: InChIKey=HVBUJINZQKNMFV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50493799   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Reverse transcriptase


(Human immunodeficiency virus 1)		BDBM50493799
PNG
(CHEMBL2443098)
Show SMILES CCc1c(nc(SCc2ccc(OC)cc2)[nH]c1=O)C(=O)c1cccc(F)c1
Show InChI InChI=1S/C21H19FN2O3S/c1-3-17-18(19(25)14-5-4-6-15(22)11-14)23-21(24-20(17)26)28-12-13-7-9-16(27-2)10-8-13/h4-11H,3,12H2,1-2H3,(H,23,24,26)
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 190n/an/an/an/an/an/a



Fudan University

Curated by ChEMBL


Assay Description
Inhibition of recombinant wild type HIV-1 reverse transcriptase p66/p51 expressed in Escherichia coli JM109 using poly(rA)/oligo(dT)16 (1:1.2) as tem...

Bioorg Med Chem 21: 6477-83 (2013)


Article DOI: 10.1016/j.bmc.2013.08.040
BindingDB Entry DOI: 10.7270/Q2KK9FRD
More data for this
Ligand-Target Pair